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Article

Association Study Between Promoter Polymorphisms of ADAM17 and Progression of Sepsis.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2016

Shao Yiming, He Junbing, Chen Feng, Cai Yujie, Zhao Jianghao, Lin Yao, Yin Zihan, Tao Hua, Shao Xin, Huang Pengru, Yin Mingkang, Zhang Wenying, Liu Zhou, Cui Lili

Abstract excerpt

BACKGROUND: A disintegrin and metalloproteinase 17 (ADAM17) has been confirmed to play a significant role in the pathogenesis of sepsis. However, little is known about the clinical relevance of ADAM17 polymorphisms to sepsis onset and development. METHODS: This study analyzed the associations of five ADAM17 promoter polymorphisms (rs55790676, rs12692386, rs11684747, rs1524668 and rs11689958) with sepsis (370...

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Share to ADAM17 Protein
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Share to Interleukin-1beta
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Source

Identifiers

PMID: 27607600
DOI: 10.1159/000447830

Genes

ADAM17
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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