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Differential expression of lung adenocarcinoma transcriptome with signature of tobacco exposure

20 Jun 2020

Abstract excerpt

Smoking accounts for almost 80-90% of lung cancer cases, which is also the most frequent cause of cancer-related deaths in humans. With over 60 carcinogens in tobacco smoke, cells dividing at the time of carcinogen exposure are at particular risk of neoplasia. The present study aimed to investigate global gene expression differences in lung adenocarcinoma (LUAD) tumour samples of current smokers and non-smokers,...

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PMID: 32564237
DOI: 10.1007/s13353-020-00569-1

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