Identification of novel OCT4 genetic variant associated with the risk of chronic hepatitis B in a Korean population.

doi:10.1111/liv.13245

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Article

Identification of novel OCT4 genetic variant associated with the risk of chronic hepatitis B in a Korean population.

Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2017

Shin Joong-Gon, Cheong Hyun Sub, Lee Kwanghyun, Ju Bong-Gun, Lee Jeong-Hoon, Yu Su Jong, Yoon Jung-Hwan, Cheong Jae Youn, Cho Sung Won, Park Neung Hwa, Namgoong Suhg, Kim Lyoung Hyo, Kim Yoon Jun, Shin Hyoung Doo

Abstract excerpt

BACKGROUND & AIMS: Hepatitis B viral infection is a serious risk factor for chronic hepatitis B (CHB), cirrhosis and hepatocellular carcinoma. Recently, several genome-wide association studies (GWASs) have been conducted to identify important genetic variant associated with the risk of CHB. In our previous GWAS, TCF19 was identified as one of the susceptibility genes for CHB risk (P=4.2×10-9 at rs1419881). In...

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PMID: 27596359
DOI: 10.1111/liv.13245

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TCF19

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