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Combined effects of AHR, CYP1A1, and XRCC1 genotypes and prenatal maternal smoking on infant birth size: Biomarker assessment in the Hokkaido Study.

Reproductive toxicology (Elmsford, N.Y.) - 1 Oct 2016

Kobayashi Sumitaka, Sata Fumihiro, Sasaki Seiko, Braimoh Titilola Serifat, Araki Atsuko, Miyashita Chihiro, Goudarzi Houman, Kobayashi Sachiko, Kishi Reiko

Abstract excerpt

OBJECTIVES: We investigated the individual and combined effects of maternal polymorphisms encoding the aromatic hydrocarbon receptor (AHR; rs2066853), cytochrome P450 (CYP) 1A1 (rs1048963), and the X-ray-complementing gene 1 (XRCC1; rs1799782) and prenatal smoking in relation to infant birth size. METHODS: Totally, 3263 participants (1998 non-smokers and 1265 smokers) were included in the study between 2003 and...

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Source

Identifiers

PMID: 27592400
DOI: 10.1016/j.reprotox.2016.08.020

Genes

AHR
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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