Article
Effects of maternal 5,10-methylenetetrahydrofolate reductase C677T and A1298C Polymorphisms and tobacco smoking on infant birth weight in a Japanese population.
Journal of epidemiology - 1 Jan 2012
Yila Thamar Ayo, Sasaki Seiko, Miyashita Chihiro, Braimoh Titilola Serifat, Kashino Ikuko, Kobayashi Sumitaka, Okada Emiko, Baba Toshiaki, Yoshioka Eiji, Minakami Hisanori, Endo Toshiaki, Sengoku Kazuo, Kishi Reiko
Abstract excerpt
BACKGROUND: Intracellular folate hemostasis depends on the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene. Because 5,10-MTHFR 677TT homozygosity and tobacco smoking are associated with low folate status, we tested the hypothesis that smoking in mothers with 5,10-MTHFR C677T or A1298C polymorphisms would be independently associated with lower birth weight among their offspring. METHODS: We assessed 1784...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.