Article
Dioxin-metabolizing genes in relation to effects of prenatal dioxin levels and reduced birth size: The Hokkaido study.
Reproductive toxicology (Elmsford, N.Y.) - 1 Jan 2017
Kobayashi Sumitaka, Sata Fumihiro, Miyashita Chihiro, Sasaki Seiko, Ban Susumu, Araki Atsuko, Goudarzi Houman, Kajiwara Jumboku, Todaka Takashi, Kishi Reiko
Abstract excerpt
OBJECTIVES: We investigated the effects of maternal polymorphisms in 3 genes encoding dioxin-metabolizing enzymes in relation to prenatal dioxin levels on infant birth size in Japan. METHODS: We examined the relationship between dioxin exposure and birth size in relation to the polymorphisms in the genes encoding aromatic hydrocarbon receptor (AHR [G>A, Arg554Lys]), cytochrome P450 (CYP) 1A1 (T6235C), and...
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