Article
Variants in LTA, TNF, IL1B and IL10 genes associated with the clinical course of sepsis.
Immunologic research - 1 Dec 2016
Montoya-Ruiz Carolina, Jaimes Fabián A, Rugeles Maria T, López Juan Álvaro, Bedoya Gabriel, Velilla Paula A
Abstract excerpt
The aim of this study was to explore the association between some SNPs of the TNF, LTA, IL1B and IL10 genes with cytokine concentrations and clinical course in Colombian septic patients. We conducted a cross-sectional study to genotype 415 septic patients and 205 patients without sepsis for the SNPs -308(G/A) rs1800629 of TNF; +252 (G/A) rs909253 of LTA; -511(A/G) rs16944 and +3953(C/T) rs1143634 of IL1B; and...
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