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Article

Tumor necrosis factor (TNF) and lymphotoxin-alpha (LTA) single nucleotide polymorphisms: importance in ARDS in septic pediatric critically ill patients.

Human immunology - 1 Jun 2012

Azevedo Z M, Moore D B, Lima F C, Cardoso C C, Bougleux R, Matos G I, Luz R A, Xavier-Elsas P, Sampaio E P, Gaspar-Elsas M I, Moraes M O

Abstract excerpt

Accumulating evidence indicates that genetic background influences the outcome of sepsis, which despite medical advances continues to be a major cause of morbidity and mortality. This study aimed to evaluate the influence of SNPs LTA +252A>G, TNF-863C>A and TNF-308G>A on susceptibility to sepsis,...

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Source

Identifiers

PMID: 22507624
DOI: 10.1016/j.humimm.2012.03.007

Genes

TNF
LTA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22507624-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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