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Article

Calorie restriction reduces biomarkers of cellular senescence in humans

14 Nov 2023

Abstract excerpt

Calorie restriction (CR) with adequate nutrient intake is a potential geroprotective intervention. To advance this concept in humans, we tested the hypothesis that moderate CR in healthy young-to-middle-aged individuals would reduce circulating biomarkers of cellular senescence, a fundamental mechanism of aging and aging-related conditions. Using plasma specimens from the Comprehensive Assessment of Long-term...

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PMID: 37961856
DOI: 10.1111/acel.14038

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