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Stem cell insights into human trophoblast lineage differentiation

2 Sept 2016

Abstract excerpt

BACKGROUND: The human placenta is vital for fetal development, yet little is understood about how it forms successfully to ensure a healthy pregnancy or why this process is inadequate in 1 in 10 pregnancies, leading to miscarriage, intrauterine growth restriction or preeclampsia. Trophoblasts are placenta-specific epithelial cells that maximize nutrient exchange. All trophoblast lineages are thought to arise from...

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PMID: 27591247
DOI: 10.1093/humupd/dmw026

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