Article
Mutation of inhibitory helix-loop-helix protein Id3 causes γδ T-cell lymphoma in mice.
Blood - 16 Dec 2010
Li Jun, Maruyama Takashi, Zhang Pin, Konkel Joanne E, Hoffman Victoria, Zamarron Brian, Chen Wanjun
Abstract excerpt
Human γδ T-cell lymphoma is a rare clinicopathologic entity with aggressive course and poor prognosis. The etiology and pathogenesis of γδ T-cell lymphoma is unknown. We show here that mice with deficiency in inhibitory helix-loop-helix protein Id3 (Id3(-/-)) developed γδ T-cell lymphoma that res...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
