Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between polymorphisms in xenobiotic detoxification-related genes with prognosis of epithelial ovarian cancer.

Medical oncology (Northwood, London, England) - 1 Oct 2016

Carron Juliana, Brito Angelo Borsarelli Carvalho, Torelli Ana Carolina Mourão, Oliveira Cristiane, Derchain Sophie Françoise Mauricette, Lima Carmen Silvia Passos, Lourenço Gustavo Jacob

Abstract excerpt

This study aimed to evaluate whether GSTM1 and GSTT1 (presents or nulls), GSTP1 c.313A>G and NQO2 c.-102A>C polymorphisms, involved in xenobiotic detoxification pathways, alter outcomes of epithelial ovarian cancer (EOC) patients. DNA from 84 EOC patients diagnosed at the University of Campinas Academic Hospital from January 1995 and July 2007 was analyzed by polymerase chain reaction and restriction fragment...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Ovarian Epithelial
Share to Glutathione S-Transferase pi

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glutathione Transferase

Share to Inactivation, Metabolic

Share to Neoplasms, Glandular and Epithelial

Share to Ovarian Neoplasms

Share to Quinone Reductases

Share to Xenobiotics

Source

Identifiers

PMID: 27586145
DOI: 10.1007/s12032-016-0819-8

Genes

GSTT1
NQO2
GSTM1
GSTP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between polymorphisms in xenobiotic detoxification-related genes with prognosis of epithelial ovarian cancer.PMID 27586145Read ↗

Platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma: glutathione S-transferase genetic polymorphisms as predictive biomarkers of disease outcome.Semantic proximity Read ↗

Genetic variants as ovarian cancer first-line treatment hallmarks: A systematic review and meta-analysis.Semantic proximity Read ↗

Pharmacogenomics of Cisplatin-Based Chemotherapy in Ovarian Cancer Patients of Different Ethnic OriginsSemantic proximity Read ↗

Improvement of a predictive model in ovarian cancer patients submitted to platinum-based chemotherapy: implications of a GST activity profile.Semantic proximity Read ↗

Glutathione S-transferase M1, T1, and P1 polymorphisms and ovarian cancer risk: a meta-analysis.Semantic proximity Read ↗

Glutathione S-transferases deletions may act as prognosis and therapeutic markers in breast cancer.Semantic proximity Read ↗

Impact of xenobiotic-metabolizing gene polymorphisms on breast cancer risk in South Indian women.Semantic proximity Read ↗

Polymorphisms in genes involved in drug detoxification and clinical outcomes of anthracycline-based neoadjuvant chemotherapy in Chinese Han breast cancer patients.Semantic proximity Read ↗

Polymorphisms of xenobiotic-metabolizing and transporter genes and the risk of gastric and colorectal cancer in an admixed population of Brazil.Semantic proximity Read ↗

Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk.Semantic proximity Read ↗

GSTT1 and GSTM1 polymorphisms predict treatment outcome for acute myeloid leukemia: a systematic review and meta-analysis.Semantic proximity Read ↗

Association between GSTP1, GSTM1 and GSTT1 polymorphisms involved in xenobiotic metabolism and head and neck cancer development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.