Article
Glutathione S-transferase M1, T1, and P1 polymorphisms and ovarian cancer risk: a meta-analysis.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jul 2010
Economopoulos Konstantinos P, Sergentanis Theodoros N, Vlahos Nikos F
Abstract excerpt
INTRODUCTION: Cytosolic glutathione S-transferase (GST) comprises multiple isoenzymes that catalyze reactions between glutathione and lipophilic compounds with electrophilic centers, resulting in the neutralization of toxic compounds, xenobiotics, and products of oxidative stress. Several studies have examined whether GST polymorphisms (GSTM1 null/present genotype, GSTT1 null/present genotype, and GSTP1...
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