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Lack of evidence for germline <i>RNF43</i> mutations in patients with serrated polyposis syndrome from a large multinational study

31 Aug 2016

Abstract excerpt

Serrated polyposis syndrome (SPS) is characterised by the occurrence of multiple serrated polyps in the large bowel. Defined clinically by the 2010 revised WHO, SPS is associated with an increased risk of colorectal cancer (CRC) for affected individuals and their first-degree relatives. Yan et al 1 recently reported their findings from whole-exome sequencing (WES) of six individuals with SPS from four families,...

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PMID: 27582512
DOI: 10.1136/gutjnl-2016-312773

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Lack of evidence for germline <i>RNF43</i> mutations in patients with serrated polyposis syndrome from a large multinational studyPMID 27582512Read ↗

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