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Article

Anti-CD48 Monoclonal Antibody Attenuates Experimental Autoimmune Encephalomyelitis by Limiting the Number of Pathogenic CD4+ T Cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2016

McArdel Shannon L, Brown Daniel R, Sobel Raymond A, Sharpe Arlene H

Abstract excerpt

CD48 (SLAMF2) is an adhesion and costimulatory molecule constitutively expressed on hematopoietic cells. Polymorphisms in CD48 have been linked to susceptibility to multiple sclerosis (MS), and altered expression of the structurally related protein CD58 (LFA-3) is associated with disease remission in MS. We examined CD48 expression and function in experimental autoimmune encephalomyelitis (EAE), a mouse model of...

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Share to Antibodies, Monoclonal
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Encephalomyelitis, Autoimmune, Experimental

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Source

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Identifiers

PMID: 27581174
DOI: 10.4049/jimmunol.1600706
PMCID: PMC5356934

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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