Article
p150/95 (CD11c/CD18) expression is required for the development of experimental autoimmune encephalomyelitis.
The American journal of pathology - 1 Jun 2007
Bullard Daniel C, Hu Xianzhen, Adams Jillian E, Schoeb Trenton R, Barnum Scott R
Abstract excerpt
p150/95 (CD11c/CD18, CR4) is a member of the beta(2)-integrin family of adhesion molecules and is considered an important phagocytic receptor. The role of p150/95 in the development of central nervous system demyelinating diseases, including multiple sclerosis, remains unexplored. To determine p150/95-mediated mechanisms in experimental autoimmune encephalomyelitis (EAE), we performed EAE using CD11c-deficient...
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