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Article

Analysis of exome sequencing data sets reveals structural variation in the coding region of ABO in individuals of African ancestry.

Transfusion - 1 Nov 2016

Fox Keolu, Johnsen Jill M, Coe Bradley P, Frazar Chris D, Reiner Alexander P, Eichler Evan E, Nickerson Deborah A

Abstract excerpt

BACKGROUND: ABO is a blood group system of high clinical significance due to the prevalence of ABO variation that can cause major, potentially life-threatening, transfusion reactions. STUDY DESIGN AND METHODS: Using multiple large-scale next-generation sequence data sets, we demonstrate the application of read-depth approaches to discover previously unsuspected structural variation (SV) in the ABO gene in...

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Identifiers

PMID: 27580710
DOI: 10.1111/trf.13797

Genes

ABO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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