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Article

Detecting serologically difficult ABO blood groups using single-molecule real-time sequencing technology.

Vox sanguinis - 1 Oct 2024

Wang Zhe, Chu Yushuang, Xiao Yanlin, Bian Maohong

Abstract excerpt

BACKGROUND AND OBJECTIVES: Recently, third-generation long-read sequencing technology has been increasingly applied to the detection of various blood group systems. Because of its long read length and use of single-molecule sequencing, it is capable of obtaining the sequences of blood group genes in their entirety as well as of distinguishing haplotypes. Therefore, here, we collected ABO blood group samples that...

Topics

Humans
ABO Blood-Group System
Female
Male
Blood Grouping and Crossmatching
Haplotypes
Alleles
Polymorphism, Single Nucleotide
Sequence Analysis, DNA

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39137927
DOI: 10.1111/vox.13721

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-39137927-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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