Article
ABO allele-level frequency estimation based on population-scale genotyping by next generation sequencing.
BMC genomics - 20 May 2016
Lang Kathrin, Wagner Ines, Schöne Bianca, Schöfl Gerhard, Birkner Kerstin, Hofmann Jan A, Sauter Jürgen, Pingel Julia, Böhme Irina, Schmidt Alexander H, Lange Vinzenz
Abstract excerpt
BACKGROUND: The characterization of the ABO blood group status is vital for blood transfusion and solid organ transplantation. Several methods for the molecular characterization of the ABO gene, which encodes the alleles that give rise to the different ABO blood groups, have been described. However, the application of those methods has so far been restricted to selected samples and not been applied to...
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