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A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis

31 Aug 2016

Abstract excerpt

Recent studies have shown that a large proportion of patients classified as essential thrombocythemia (ET) actually have early primary prefibrotic myelofibrosis (prePMF), which implies an inferior prognosis as compared to patients being diagnosed with so-called genuine or true ET. According to the World Health Organization (WHO) 2008 classification, bone marrow histology is a major component in the distinction...

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PMID: 27579896
DOI: 10.1371/journal.pone.0161570

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