Article
A globally applicable "triple A" risk model for essential thrombocythemia based on Age, Absolute neutrophil count, and Absolute lymphocyte count.
American journal of hematology - 1 Dec 2023
Tefferi Ayalew, Loscocco Giuseppe G, Farrukh Faiqa, Szuber Natasha, Mannelli Francesco, Pardanani Animesh, Hanson Curtis A, Ketterling Rhett P, De Stefano Valerio, Carobbio Alessandra, Barbui Tiziano, Guglielmelli Paola, Gangat Naseema, Vannucchi Alessandro M
Abstract excerpt
We examined the individual prognostic contribution of absolute neutrophil (ANC), lymphocyte (ALC), and monocyte (AMC) counts, on overall (OS), leukemia-free (LFS), and myelofibrosis-free (MFFS) survival in essential thrombocythemia (ET). Informative cases (N = 598; median age 59 years; females 62%) were retrospectively accrued from a Mayo Clinic database: JAK2 59%, CALR 27%, triple-negative 11%, and MPL 3%;...
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