Article
Pre-fibrotic/early primary myelofibrosis vs. WHO-defined essential thrombocythemia: The impact of minor clinical diagnostic criteria on the outcome of the disease.
American journal of hematology - 1 Sept 2017
Jeryczynski Georg, Thiele Jürgen, Gisslinger Bettina, Wölfler Albert, Schalling Martin, Gleiß Andreas, Burgstaller Sonja, Buxhofer-Ausch Veronika, Sliwa Thamer, Schlögl Ernst, Geissler Klaus, Krauth Maria-Theresa, Nader Alexander, Vesely Michael, Simonitsch-Klupp Ingrid, Müllauer Leonhard, Beham-Schmid Christine, Gisslinger Heinz
Abstract excerpt
The 2016 revised WHO criteria for the diagnosis of pre-fibrotic/early primary myelofibrosis (pre-PMF) require at least one of the following four borderline expressed minor clinical criteria: anemia, leukocytosis, elevated lactate dehydrogenase and splenomegaly. In this study, we evaluated the relative frequency of these four criteria in a group of 170 pre-PMF patients and compared them to 225 ET cases. More than...
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