Article
Evidence that prefibrotic myelofibrosis is aligned along a clinical and biological continuum featuring primary myelofibrosis.
PloS one - 1 Jan 2012
Barosi Giovanni, Rosti Vittorio, Bonetti Elisa, Campanelli Rita, Carolei Adriana, Catarsi Paolo, Isgrò Antonina M, Lupo Letizia, Massa Margherita, Poletto Valentina, Viarengo Gianluca, Villani Laura, Magrini Umberto
Abstract excerpt
PURPOSE: In the WHO diagnostic classification, prefibrotic myelofibrosis (pre-MF) is included in the category of primary myelofibrosis (PMF). However, strong evidence for this position is lacking. PATIENTS AND METHODS: We investigated whether pre-MF may be aligned along a clinical and biological continuum in 683 consecutive patients who received a WHO diagnosis of PMF. RESULTS: As compared with PMF-fibrotic type,...
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