Article
Shedding light on the performance of a pyrosequencing assay for drug-resistant tuberculosis diagnosis.
BMC infectious diseases - 31 Aug 2016
Georghiou Sophia B, Seifert Marva, Lin Shou-Yean, Catanzaro Donald, Garfein Richard S, Jackson Roberta L, Crudu Valeriu, Rodrigues Camilla, Victor Thomas C, Catanzaro Antonino, Rodwell Timothy C
Abstract excerpt
BACKGROUND: Rapid molecular diagnostics, with their ability to quickly identify genetic mutations associated with drug resistance in Mycobacterium tuberculosis clinical specimens, have great potential as tools to control multi- and extensively drug-resistant tuberculosis (M/XDR-TB). The Qiagen PyroMark Q96 ID system is a commercially available pyrosequencing (PSQ) platform that has been validated for rapid...
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