Article
Frequency and Distribution of Tuberculosis Resistance-Associated Mutations between Mumbai, Moldova, and Eastern Cape.
Antimicrobial agents and chemotherapy - 1 Jul 2016
Georghiou S B, Seifert M, Catanzaro D, Garfein R S, Valafar F, Crudu V, Rodrigues C, Victor T C, Catanzaro A, Rodwell T C
Abstract excerpt
Molecular diagnostic assays, with their ability to rapidly detect resistance-associated mutations in bacterial genes, are promising technologies to control the spread of drug-resistant tuberculosis (DR-TB). Sequencing assays provide detailed information for specific gene regions and can help diagnostic assay developers prioritize mutations for inclusion in their assays. We performed pyrosequencing of seven...
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