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Article

Minichromosome maintenance complex component 8 mutations cause primary ovarian insufficiency.

Fertility and sterility - 1 Nov 2016

Dou Xiaoyun, Guo Ting, Li Guangyu, Zhou LiGuang, Qin Yingying, Chen Zi-Jiang

Abstract excerpt

OBJECTIVE: To investigate whether mutations in the minichromosome maintenance complex component 8 (MCM8) gene were present in 192 patients with sporadic primary ovarian insufficiency (POI). DESIGN: Retrospective case-control cohort study. SETTING: University-based reproductive medicine center. PATIENT(S): A total of 192 patients with sporadic POI and 312 control women with regular menstruation (192 age-matched...

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Identifiers

PMID: 27573988
DOI: 10.1016/j.fertnstert.2016.08.018

Genes

MCM8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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