Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetics of Primary Ovarian Insufficiency in the Next-Generation Sequencing Era

19 Feb 2019

Abstract excerpt

Abstract Primary ovarian insufficiency (POI) is characterized by amenorrhea, increased follicle-stimulating hormone (FSH) levels, and hypoestrogenism, leading to infertility before the age of 40 years. Elucidating the cause of POI is a key point for diagnosing and treating affected women. Here, we review the genetic etiology of POI, highlighting new genes identified in the last few years using next-generation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Renal and related cancers
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32099950
DOI: 10.1210/jendso/bvz037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics of Primary Ovarian Insufficiency in the Next-Generation Sequencing EraPMID 32099950Read ↗

Genetics of ovarian insufficiency and defects of folliculogenesis.Semantic proximity Read ↗

Genetic landscape of a large cohort of Primary Ovarian Insufficiency: New genes and pathways and implications for personalized medicineSemantic proximity Read ↗

Genetic Landscape of a Cohort of 120 Patients with Diminished Ovarian Reserve: Correlation with InfertilitySemantic proximity Read ↗

Targeted Next-Generation Sequencing Indicates a Frequent Oligogenic Involvement in Primary Ovarian Insufficiency Onset.Semantic proximity Read ↗

Selected Genetic Factors Associated with Primary Ovarian Insufficiency.Semantic proximity Read ↗

Next Generation Sequencing Should Be Proposed to Every Woman With “Idiopathic” Primary Ovarian InsufficiencySemantic proximity Read ↗

Screening of targeted panel genes in Brazilian patients with primary ovarian insufficiencySemantic proximity Read ↗

Genetic variants in diminished ovarian reserve and premature ovarian insufficiency: implications for assisted reproductive outcomes.Semantic proximity Read ↗

Genetics of primary ovarian insufficiency: new developments and opportunities.Semantic proximity Read ↗

Landscape of pathogenic mutations in premature ovarian insufficiency.Semantic proximity Read ↗

Primary ovarian insufficiency, meiosis and DNA repair.Semantic proximity Read ↗

An exome-wide exploration of cases of primary ovarian insufficiency uncovers novel sequence variants and candidate genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.