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Novel pathogenic mutations in minichromosome maintenance complex component 9 (MCM9) responsible for premature ovarian insufficiency.

Fertility and sterility - 1 Apr 2020

Guo Ting, Zheng Ye, Li Guangyu, Zhao Shidou, Ma Jinlong, Qin Yingying

Abstract excerpt

OBJECTIVE: To investigate whether mutations in the minichromosome maintenance complex component 9 (MCM9) gene were present in 192 patients with sporadic premature ovarian insufficiency (POI) of Chinese descent. DESIGN: Genetic and functional study. SETTING: University-based reproductive medicine center. PATIENT(S): A total of 192 patients with sporadic POI and 192 control women with regular menstruation....

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PMID: 32145932
DOI: 10.1016/j.fertnstert.2019.11.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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