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Article

PRMT1 promotes neuroblastoma cell survival through ATF5

15 May 2020

Abstract excerpt

Aberrant expression of protein arginine methyltransferases (PRMTs) has been implicated in a number of cancers, making PRMTs potential therapeutic targets. But it remains not well understood how PRMTs impact specific oncogenic pathways. We previously identified PRMTs as important regulators of cell growth in neuroblastoma, a deadly childhood tumor of the sympathetic nervous system. Here, we demonstrate a critical...

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PMID: 32415090
DOI: 10.1038/s41389-020-0237-9

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