Article
Gene sequencing and variable site analyzing of coding region of two enterovirus A71 isolates with different clinical phenotypes.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Nov 2016
Xie Bing-Yu, Xu Chao, Xiong Qing, Zhu Meng, Duan Hao, Wang Yu-Ya, Zhang Hao, Ni Xue-Fei, Wang Ling-Hang, Li Xing-Wang, Shen Tao, Peng Yi-Hong
Abstract excerpt
Currently, it is still controversial that if the pathogenicity of EV-A71 causing severe or mild hand, foot, and mouth disease (HFMD) is associated with viral nucleotide or amino acid sequence(s). In this study, 19 clinical strains were detected in samples from diagnosed patients of EV-A71-caused HFMD with mild or severe symptoms. Then, VP1-2A fragment sequences of 19 EV-A71 isolates were determined, the...
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