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Molecular Analysis of Virulent Determinants of Enterovirus 71

19 Oct 2011

Abstract excerpt

Enterovirus 71 (EV71) is the most important causative agent of hand, foot and mouth disease (HFMD) in children. In most cases, it is a self-limiting illness. However some EV71 infectious cases can develop severe clinical outcomes, such as encephalitis, meningitis, poliomyelitis like paralysis, and even death. To identify the determinants of virulence, the deduced amino acid sequence of polyprotein and nucleotide...

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PMID: 22039449
DOI: 10.1371/journal.pone.0026237

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