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Article

miR-106a promotes cardiac hypertrophy by targeting mitofusin 2.

Journal of molecular and cellular cardiology - 1 Oct 2016

Guan Xiaoxiang, Wang Lu, Liu Zhenhong, Guo Xiaofei, Jiang Yuan, Lu Ying, Peng Yanli, Liu Tianhua, Yang Baofeng, Shan Hongli, Zhang Yong, Xu Chaoqian

Abstract excerpt

Pathological cardiac hypertrophy is a main factor leading to heart failure and associated sudden death. Improved understanding of the underlying molecular mechanisms should aid better treatment of the disease. This study aimed to test our hypothesis that a microRNA miR-106a played an important role in the development of cardiac hypertrophy through targeting mitofusin 2 (Mfn2), a mitochondrial fusion protein known...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27565029
DOI: 10.1016/j.yjmcc.2016.08.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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