Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression Profile of microRNAs in Hypertrophic Cardiomyopathy and Effects of microRNA-20 in Inducing Cardiomyocyte Hypertrophy Through Regulating Gene MFN2

11 Jul 2019

Abstract excerpt

Myocardial hypertrophy is an important cause of heart failure and sudden death. Studies have shown that Mitofusin-2 (MFN2) is downregulated in myocardial hypertrophy, but the upstream regulation mechanism underlying its downexpression in cardiomyocytes is still unclear. This study aims to identify the expression profile of microRNAs (miRNAs) in hypertrophic cardiomyopathy (HCM) and explore the function of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy and Myosin Studies
Share to MicroRNA in disease regulation
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31295012
DOI: 10.1089/dna.2019.4731

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression Profile of microRNAs in Hypertrophic Cardiomyopathy and Effects of microRNA-20 in Inducing Cardiomyocyte Hypertrophy Through Regulating Gene MFN2PMID 31295012Read ↗

miR-106a promotes cardiac hypertrophy by targeting mitofusin 2.Semantic proximity Read ↗

New Insights into the Functions of MicroRNAs in Cardiac Fibrosis: From Mechanisms to Therapeutic StrategiesSemantic proximity Read ↗

MicroRNAs in Hypertrophic, Arrhythmogenic and Dilated CardiomyopathySemantic proximity Read ↗

Unveiling miRNA Biomarkers for Hypertrophic Cardiomyopathy through Integrated Bioinformatics and Machine Learning AnalysisSemantic proximity Read ↗

Cardiomyopathies: The Role of Non-Coding RNAsSemantic proximity Read ↗

LncRNAs in cardiac hypertrophy: From basic science to clinical applicationSemantic proximity Read ↗

Identification of key genes for hypertrophic cardiomyopathy using integrated network analysis of differential lncRNA and gene expressionSemantic proximity Read ↗

The roles of long noncoding RNAs in myocardial pathophysiologySemantic proximity Read ↗

Small RNA-sequencing identified the potential roles of neuron differentiation and MAPK signaling pathway in dilated cardiomyopathySemantic proximity Read ↗

MicroRNAs challenge the status quo of therapeutic targeting.Semantic proximity Read ↗

MiRNA-Regulated Pathways for Hypertrophic Cardiomyopathy: Network-Based Approach to Insight into PathogenesisSemantic proximity Read ↗

Circular RNA circRNA_000203 aggravates cardiac hypertrophy via suppressing miR-26b-5p and miR-140-3p binding to Gata4Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.