Article

MicroRNA-129-5p targets keap-1 to protect against cardiomyocyte hypertrophy via Nrf2 pathway

2020-01-02

Abstract excerpt

<title>Abstract</title> <p>Background: Cardiac hypertrophy is a common pathological process of many cardiac diseases and persistent cardiac hypertrophy is the main cause of heart failure and sudden cardiogenic death. It is of great value to elucidate the mechanism of cardiac hypertrophy for better prevention and treatment. <h4>Methods:</h4> The protein levels were measured by western blotting or RT-qPCR. cardiomy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 00915155-c783-57ef-88c3-736804f56b42
DOI: 10.21203/rs.2.19838/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-129-5p targets keap-1 to protect against cardiomyocyte hypertrophy via Nrf2 pathwayDOI 10.21203/rs.2.19838/v1Read

MiR‐26a‐5p alleviates cardiac hypertrophy and dysfunction via targeting ADAM17Semantic proximity Read

LncRNAs in cardiac hypertrophy: From basic science to clinical applicationSemantic proximity Read

FOXO3a-dependent PARKIN negatively regulates cardiac hypertrophy by restoring mitophagySemantic proximity Read

Egr-1 mediated cardiac miR-99 family expression diverges physiological hypertrophy from pathological hypertrophySemantic proximity Read

NRF1-enhanced miR-4458 alleviates cardiac hypertrophy through releasing TTP-inhibited TFAM.Semantic proximity Read

Discovery of zerumbone as a new agent for cardiac hypertrophy by high-throughput screening using human embryonic stem cell-derived cardiomyocytesSemantic proximity Read

Molecular targets and regulators of cardiac hypertrophy.Semantic proximity Read

Extracellular vesicular microRNAs and cardiac hypertrophySemantic proximity Read

Krüppel-like Factors Hypertrophy Modulation Following Isoproterenol-Induced Myocardial DamageSemantic proximity Read

Heart-enriched long noncoding RNA NPPA-AS1 regulates pathological cardiac hypertrophy by initiating a EP300-GATA4 axisSemantic proximity Read

Recent discoveries of the role of histone modifications and related inhibitors in pathological cardiac hypertrophySemantic proximity Read

PHD Finger Protein 19 Promotes Cardiac Hypertrophy via Epigenetically Regulating SIRT2Semantic proximity Read