Article
DNA methylation signature of intergenic region involves in nucleosome remodeler DDM1-mediated repression of aberrant gene transcriptional read-through.
Journal of genetics and genomics = Yi chuan xue bao - 20 Aug 2016
Yan Xiaojing, Dong Xiaomei, Liu Lei, Yang Yongqing, Lai Jinsheng, Guo Yan
Abstract excerpt
The strict and efficient transcription termination is required to prevent production of aberrant read-through transcripts that may cause transcriptional interference at neighboring genes. However, the exact regulatory mechanism remains poorly understood. Through a genetic screening of a LUCIFERASE (LUC) reporter system, we found that Arabidopsis nucleosome remodeler DECREASE IN DNA METHYLATION1 (DDM1) is a key...
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