Article
DNA Methylation and Histone H1 Jointly Repress Transposable Elements and Aberrant Intragenic Transcripts.
Molecular cell - 16 Jan 2020
Choi Jaemyung, Lyons David B, Kim M Yvonne, Moore Jonathan D, Zilberman Daniel
Abstract excerpt
DNA methylation and histone H1 mediate transcriptional silencing of genes and transposable elements, but how they interact is unclear. In plants and animals with mosaic genomic methylation, functionally mysterious methylation is also common within constitutively active housekeeping genes. Here, we show that H1 is enriched in methylated sequences, including genes, of Arabidopsis thaliana, yet this enrichment is...
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