Article
Functional characterization of variations on regulatory motifs.
PLoS genetics - 7 Mar 2008
Lapidot Michal, Michal Lapidot, Mizrahi-Man Orna, Pilpel Yitzhak
Abstract excerpt
Transcription factors (TFs) regulate gene expression through specific interactions with short promoter elements. The same regulatory protein may recognize a variety of related sequences. Moreover, once they are detected it is hard to predict whether highly similar sequence motifs will be recognized by the same TF and regulate similar gene expression patterns, or serve as binding sites for distinct regulatory...
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