Article
PromoLign: a database for upstream region analysis and SNPs.
Human mutation - 1 Jun 2004
Zhao Tao, Chang Li-Wei, McLeod Howard L, Stormo Gary D
Abstract excerpt
The study of transcriptional regulation at the genomic level has been hindered by the lack of functional annotation in the putative regulatory regions. Phylogenetic footprinting, in which cross-species sequence alignment among orthologous genes is applied to locate conserved sequence blocks, is an effective strategy to attack this problem. Single nucleotide polymorphisms (SNPs) in transcription factor (TF)...
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