Combining label-free cell phenotypic profiling with computational approaches for novel drug discovery.

Abstract excerpt

INTRODUCTION: Drug discovery is a long and costly process. Innovations and paradigm shifts are essential for continuous improvement in the productivity of pharmaceutical R&D. AREAS COVERED: The author reviews the progress of label-free cell phenotypic and computational approaches in early drug discovery since 2004 and proposes a novel paradigm, which combines both approaches. EXPERT OPINION: Label-free cell...

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