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Article

Characterisation of the global transcriptional response to heat shock and the impact of individual genetic variation.

Genome medicine - 24 Aug 2016

Humburg Peter, Maugeri Narelle, Lee Wanseon, Mohr Bert, Knight Julian C

Abstract excerpt

BACKGROUND: The heat shock transcriptional response is essential to effective cellular function under stress. This is a highly heritable trait but the nature and extent of inter-individual variation in heat shock response remains unresolved. METHODS: We determined global transcription profiles of the heat shock response for a panel of lymphoblastoid cell lines established from 60 founder individuals in the Yoruba...

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Identifiers

PMID: 27553423
DOI: 10.1186/s13073-016-0345-5
PMCID: PMC4995779

Genes

HSF1
UBQLN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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