Article
Gene expression drives local adaptation in humans.
Genome research - 1 Jul 2013
Fraser Hunter B
Abstract excerpt
The molecular basis of adaptation--and, in particular, the relative roles of protein-coding versus gene expression changes--has long been the subject of speculation and debate. Recently, the genotyping of diverse human populations has led to the identification of many putative "local adaptations" that differ between populations. Here I show that these local adaptations are over 10-fold more likely to affect gene...
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