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Article

A genome-wide association study of global gene expression.

Nature genetics - 1 Oct 2007

Dixon Anna L, Liang Liming, Moffatt Miriam F, Chen Wei, Heath Simon, Wong Kenny C C, Taylor Jenny, Burnett Edward, Gut Ivo, Farrall Martin, Lathrop G Mark, Abecasis Gonçalo R, Cookson William O C

Abstract excerpt

We have created a global map of the effects of polymorphism on gene expression in 400 children from families recruited through a proband with asthma. We genotyped 408,273 SNPs and identified expression quantitative trait loci from measurements of 54,675 transcripts representing 20,599 genes in Epstein-Barr virus-transformed lymphoblastoid cell lines. We found that 15,084 transcripts (28%) representing 6,660 genes...

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Identifiers

PMID: 17873877
DOI: 10.1038/ng2109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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