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Article

High prevalence and predominance of BRCA1 germline mutations in Pakistani triple-negative breast cancer patients.

BMC cancer - 23 Aug 2016

Rashid Muhammad Usman, Muhammad Noor, Bajwa Seerat, Faisal Saima, Tahseen Muhammad, Bermejo Justo Lorenzo, Amin Asim, Loya Asif, Hamann Ute

Abstract excerpt

BACKGROUND: Women harboring BRCA1/2 germline mutations have high lifetime risk of developing breast/ovarian cancer. The recommendation to pursue BRCA1/2 testing is based on patient's family history of breast/ovarian cancer, age of disease-onset and/or pathologic parameters of breast tumors. Here, we investigated if diagnosis of triple-negative breast cancer (TNBC) independently increases risk of carrying a...

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Share to BRCA1 Protein
Share to Carcinoma, Ductal, Breast

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27553291
DOI: 10.1186/s12885-016-2698-y
PMCID: PMC4995655

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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