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Germline Mutations in BRCA1 and BRCA2 in Breast Cancer Patients with High Genetic Risk in Turkish Population

1 Jan 2019

Abstract excerpt

BACKGROUND: The guidelines recommend considering the BRCA1 and BRCA2 germline mutations in female patients with breast carcinomas. In this retrospective study, the BRCA1/2 mutation prevalence in high-risk breast carcinoma patients in a Turkish population was investigated. MATERIALS AND METHODS: In high genetic risk breast carcinoma patients, the BRCA1 and BRCA2 germline mutations were identified by applying...

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PMID: 30713775
DOI: 10.1155/2019/9645147

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