Article
Analysis of Viral Diversity in Relation to the Recency of HIV-1C Infection in Botswana.
PloS one - 1 Jan 2016
Moyo Sikhulile, Vandormael Alain, Wilkinson Eduan, Engelbrecht Susan, Gaseitsiwe Simani, Kotokwe Kenanao P, Musonda Rosemary, Tanser Frank, Essex Max, Novitsky Vladimir, de Oliveira Tulio
Abstract excerpt
BACKGROUND: Cross-sectional, biomarker methods to determine HIV infection recency present a promising and cost-effective alternative to the repeated testing of uninfected individuals. We evaluate a viral-based assay that uses a measure of pairwise distances (PwD) to identify HIV infection recency, and compare its performance with two serologic incidence assays, BED and LAg. In addition, we assess whether...
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