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Metalloproteinases and Brain Arterial Remodeling Among Individuals With and Those Without HIV Infection

22 Aug 2016

Abstract excerpt

BACKGROUND: This study tests the hypothesis that increased elastolytic activity is associated differentially with dolichoectasia in individuals with and those without human immunodeficiency virus (HIV) infection. METHODS: Large arteries from 84 autopsied brains from HIV-positive individuals and 78 autopsied brains from HIV-negative individuals were stained for metalloproteinase 2 (MMP-2), MMP-3, MMP-9, tissue...

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PMID: 27549585
DOI: 10.1093/infdis/jiw385

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