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Article

Lentivirus infection in the brain induces matrix metalloproteinase expression: role of envelope diversity.

Journal of virology - 1 Aug 2000

Johnston J B, Jiang Y, van Marle G, Mayne M B, Ni W, Holden J, McArthur J C, Power C

Abstract excerpt

Infection of the brain by lentiviruses, including human immunodeficiency virus (HIV) and feline immunodeficiency virus (FIV), causes inflammation and results in neurodegeneration. Molecular diversity within the lentivirus envelope gene has been implicated in the regulation of cell tropism and the host response to infection. Here, we examine the hypothesis that envelope sequence diversity modulates the expression...

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Identifiers

PMID: 10906175
DOI: 10.1128/jvi.74.16.7211-7220.2000
PMCID: PMC112242

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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