Article
Role of MMP-13-77A/G polymorphism in HIV-associated neurocognitive disorders patients.
Microbial pathogenesis - 1 Nov 2022
Singh HariOm, Dhotre Kishore
Abstract excerpt
Many diseases including HIV-Associated Neurocognitive Disorder (HAND) are impacted by matrix metalloproteinases (MMPs). MMP-13 play a role to cleave the collagen. MMP-13 contributes to peripheral neuropathy and induces unmyelinated axon degeneration. MMP-13-77A/G polymorphism has been associated to a lower level of MMP-13. MMP-13 have been linked to increased expression in a number of diseases including...
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