Article
Genome-wide association study in an admixed case series reveals IL12A as a new candidate in Behçet disease.
PloS one - 1 Jan 2015
Kappen Jasper H, Medina-Gomez Carolina, van Hagen P Martin, Stolk Lisette, Estrada Karol, Rivadeneira Fernando, Uitterlinden Andre G, Stanford Miles R, Ben-Chetrit Eldat, Wallace Graham R, Soylu Merih, van Laar Jan A M
Abstract excerpt
INTRODUCTION: The etiology of Behçet's disease (BD) is unknown, but widely considered an excessive T-cell mediated inflammatory response in a genetically susceptible host. Recent genome-wide association studies (GWAS) have shown limited number of novel loci-associations. The rarity and unequal di...
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