Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease.

doi:10.1038/ng.625

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease.

Nature genetics - 1 Aug 2010

Remmers Elaine F, Cosan Fulya, Kirino Yohei, Ombrello Michael J, Abaci Neslihan, Satorius Colleen, Le Julie M, Yang Barbara, Korman Benjamin D, Cakiris Aris, Aglar Oznur, Emrence Zeliha, Azakli Hulya, Ustek Duran, Tugal-Tutkun Ilknur, Akman-Demir Gulsen, Chen Wei, Amos Christopher I, Dizon Michael B, Kose Afet Akdag, Azizlerli Gulsevim, Erer Burak, Brand Oliver J, Kaklamani Virginia G, Kaklamanis Phaedon, Ben-Chetrit Eldad, Stanford Miles, Fortune Farida, Ghabra Marwen, Ollier William E R, Cho Young-Hun, Bang Dongsik, O'Shea John, Wallace Graham R, Gadina Massimo, Kastner Daniel L, Gül Ahmet

Abstract excerpt

Behçet's disease is a genetically complex disease of unknown etiology characterized by recurrent inflammatory attacks affecting the orogenital mucosa, eyes and skin. We performed a genome-wide association study with 311,459 SNPs in 1,215 individuals with Behçet's disease (cases) and 1,278 healthy controls from Turkey. We confirmed the known association of Behçet's disease with HLA-B*51 and identified a second,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Behcet Syndrome

Share to Europe

Share to Genes, MHC Class I

Share to HLA-B Antigens

Share to Interleukin-10

Share to Middle East

Share to Turkey

Source

Open in PubMed Open full text

Identifiers

PMID: 20622878
DOI: 10.1038/ng.625
PMCID: PMC2923807

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease.PMID 20622878Read ↗

Identification of susceptibility SNPs in IL10 and IL23R-IL12RB2 for Behçet's disease in Han Chinese.Semantic proximity Read ↗

The immunogenetics of Behçet's disease: A comprehensive review.Semantic proximity Read ↗

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility lociSemantic proximity Read ↗

Brief report: association of CCR1, KLRC4, IL12A-AS1, STAT4, and ERAP1 With Behçet's disease in Iranians.Semantic proximity Read ↗

Association study of IL10 and IL23R-IL12RB2 in Iranian patients with Behçet's disease.Semantic proximity Read ↗

Association Analysis of IL10, TNF-α, and IL23R-IL12RB2 SNPs with Behçet’s Disease Risk in Western AlgeriaSemantic proximity Read ↗

Investigation of the Relationships Between IL-12B and IL-23 Receptor Polymorphisms with Behçet's Disease in a Turkish Population.Semantic proximity Read ↗

A comprehensive overview on the genetics of Behçet's disease.Semantic proximity Read ↗

Single-Nucleotide Polymorphisms in IL23R-IL12RB2 (rs1495965) Are Highly Prevalent in Patients with Behcet's Uveitis and Vary Between Populations.Semantic proximity Read ↗

Dense genotyping of immune-related loci implicates host responses to microbial exposure in Behçet's disease susceptibility.Semantic proximity Read ↗

On the genetics of the Silk Route: association analysis of HLA, IL10, and IL23R-IL12RB2 regions with Behçet's disease in an Iranian population.Semantic proximity Read ↗

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.